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  • 吴昊,马江锋,吴明科,张敏,陈可泉,姜岷.非粮生物质制备生物基丁二酸的研究进展[J].广西科学,2015,22(1):20-26.    [点击复制]
  • WU Hao,MA Jiang-feng,WU Ming-ke,ZHANG Min,CHEN Ke-quan,JIANG Min.Progress in Microbial Production of Succinic Acid Using Non-food Biomass Feedstock[J].Guangxi Sciences,2015,22(1):20-26.   [点击复制]
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非粮生物质制备生物基丁二酸的研究进展
吴昊, 马江锋, 吴明科, 张敏, 陈可泉, 姜岷
0
(南京工业大学生物与制药工程学院, 江苏南京 211816)
摘要:
丁二酸(Succinic acid)是重要的碳四平台化合物,拥有巨大的潜在市场需求量。随着能源危机和粮食安全问题的日益严重,利用非粮生物质原料提高生物基丁二酸的竞争力成为研究的热点。文中从生产菌种的选育、非粮生物质原料的利用与产物提取3个方面对国内外相关研究进展进行综述,最后探讨该领域中所面临的问题与研究方向,并展望其发展前景。
关键词:  丁二酸  非粮生物质  菌种选育  发酵  提取
DOI:10.13656/j.cnki.gxkx.20150126.009
投稿时间:2015-01-05
基金项目:国家重点基础研究发展计划(973计划)项目(No.2009CB724701),国家高技术研究发展计划(863项计划)项目(No.2011AA02A203),国家自然科学基金项目(No.21076105)和江苏高校优势学科建设工程项目资助。
Progress in Microbial Production of Succinic Acid Using Non-food Biomass Feedstock
WU Hao, MA Jiang-feng, WU Ming-ke, ZHANG Min, CHEN Ke-quan, JIANG Min
(College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, Jiangsu, 211816, China)
Abstract:
Succinic acid is an important C4-platform chemical, which has huge market potential in applications.Diminishing petroleum reserves and increasing concerns on food security have resulted in worldwide interests in the study of bio-succinic acid production using non-food biomass feedstock.This article reviewed recent advances in the production of succinic acid by microbial fermentation, including discovery and screening of the succinic-acid-producing microbes, utilization of non-food biomass feedstock, and product recovery technology.Finally, we discussed the limitation of this progress and proposed the future research needs for succinic acid production using non-food biomass feedstock.
Key words:  succinic acid  non-food biomass  strain screening  fermentation  recovery

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