| 摘要: |
| 采用紫外分光光度法测定丙硫异烟胺片中丙硫异烟胺的含量。结果显示,样品在291nm处吸收最佳,在5~25μg/ml的浓度范围内与吸收度呈良好线性关系,平均回收率为99.8%(n=6),RSD=0.32%。该方法简便、快速,具有较好的重现性和稳定性与药典中方法测定结果基本一致,可以用于丙硫异烟胺片的定量分析及其生产过程中的质量控制。 |
| 关键词: 紫外分光光度法 丙硫异烟胺 含量测定 |
| DOI： |
| 投稿时间：2010-06-21 |
| 基金项目: |
|
| Analysis of Protionamide Content in Protionamide Tablets by UV Spectrophotometry |
|
LIU Wei-lin
|
| (Guangxi Institute for Food and Drug Control, Nanning, Guangxi, 530021, China) |
| Abstract: |
| The protionamide content in protionamide tablets was assayed by UV spectrophotometry. The results showed that the max absorption wavelength was 291nm.The absorption was linearly in propotion to protionamid concentration within the range of 5~25μg/ml. The average recovery was 99.80%(n=6),RSD was 0.32%. The method is simple, rapid,obtained from reproducible and stable.The detection results are consistent with that obtained from China Pharmacopeia. Therefore, this method could be applied to quantitative analysis and quality control. |
| Key words: UV spectrophotometry protionamide content determination |
