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易湘茜,谢文佩,颜栋美,余炼,范丽丽,唐云丽.白骨壤果实中抗氧化活性成分研究[J].广西科学院学报,2014,30(4):253-256. [点击复制]
- YI Xiang-xi,XIE Wen-pei,YAN Dong-mei,YU Lian,FAN Li-li,TANG Yun-li.Antioxidative Chemical Constituents from the Fruits of Avicennia marina[J].Journal of Guangxi Academy of Sciences,2014,30(4):253-256. [点击复制]
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| 白骨壤果实中抗氧化活性成分研究 |
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易湘茜1, 谢文佩1,2, 颜栋美2, 余炼2, 范丽丽1, 唐云丽1
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| (1.广西中医药大学药学院, 广西南宁 530001;2.广西大学轻工与食品工程学院, 广西南宁 530004) |
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| 摘要: |
| [目的]为获得高效的抗氧化先导化合物,对红树白骨壤(Avicennia marina)果实中化学成分进行研究。[方法]采用柱色谱和高效液相色谱及细胞定量分析方法,对白骨壤果实中抗氧化活性成分进行研究,并运用色谱分析和文献对照方法,鉴定其化学结构。[结果]从白骨壤果实中分离鉴定了4个具有抗氧化活性的单体化合物,分别为tamarixetin-3-O-β-D-glucopyranoside(1)、3,4-dihydroxyphenethylalcohol-6-O-caffeoyl-β-D-glucoside(2)、类叶升麻苷(3)、焦地黄苯乙醇甙C(4)。化合物1~4的EC50值分别为(16.0±0.98)μM,(18.5±1.47)μM,(9.5±1.09)μM和(12.0±0.89)μM。[结论]红树白骨壤果实中存在着具有强抗氧化活性成分(1~4),且上述活性成份均为首次从该物种中分离获得。 |
| 关键词: 红树 白骨壤 黄酮苷 苯乙基苷 抗氧化活性 |
| DOI： |
| 投稿时间：2014-06-10 |
| 基金项目:广西近海海洋环境科学重点实验室开放基金项目(GXKLHY13-06),广西自然科学基金项目(2014GXNSFAA118048,2012GXNSFAA053160),广西科技兴海专项项目(GXZC2014G30578KLZBC),广西中医药大学中药学博士点建设工程开放课题(201410-02),2013年广西高校重点学科和重点实验室建设项目(桂教科研2013-8-2-16)资助。 |
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| Antioxidative Chemical Constituents from the Fruits of Avicennia marina |
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YI Xiang-xi1, XIE Wen-pei1,2, YAN Dong-mei2, YU Lian2, FAN Li-li1, TANG Yun-li1
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| (1.School of Pharmaceutical Sciences, Guangxi University of Chinese Medicine, Nanning, Guangxi, 530001, China;2.College of Light Industry and Food Engineering, Guangxi University, Nanning, Guangxi, 530004, China) |
| Abstract: |
| [Objective] In order to obtain strong antioxidant compounds,the fruits of mangrove Avicennia marina were investigated.[Methods] The antioxidative constituents were isolated and analyzed by column chromatograph,HPLC and cell quantiative analysis. The structure of the constituents was identified by chromatograph analysis results and previous paper.[Results] The fruits of mangrove Avicennia marina contains one flavonoid glycoside,tamarixetin-3-β-D-glucopyranoside (1),and three known phenylethyl glycosides,3,4-dihydroxyphenethylalcohol-6-O-caffeoyl-β-D-glucoside (2),acteoside (3) and jionoside C (4).The EC50 values of compounds 1~4 were (16.0±0.98)μM,(18.5±1.47)μM,(9.5±1.09)μM,and (12.0±0.89)μM,respectively.[Conclusion] The strong antioxidant compounds were obtained from the fruits of Avicennia marina,and these compounds were obtained from the fruits of this species for the first time. |
| Key words: mangrove Avicennia marina flavonoid glycoside phenylethyl glycoside antioxidant |
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