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谢能中,王青艳,朱绮霞,秦艳,陈东,李亿,黄日波.微生物催化合成丙烯酸的研究进展[J].广西科学院学报,2013,29(3):149-153. [点击复制]
- XIE Neng-zhong,WANG Qing-yan,ZHU Qi-xia,QIN Yan,CHEN Dong,LI Yi,HUANG Ri-bo.Advances in the Research of Acrylic Acid Production by Microbial Catalysis[J].Journal of Guangxi Academy of Sciences,2013,29(3):149-153. [点击复制]
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| 微生物催化合成丙烯酸的研究进展 |
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谢能中, 王青艳, 朱绮霞, 秦艳, 陈东, 李亿, 黄日波
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| (广西科学院国家非粮生物质能源工程技术研究中心, 非粮生物质酶解国家重点实验室, 广西生物质产业化工程院, 广西生物炼制重点实验室, 广西南宁 530007) |
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| 摘要: |
| 丙烯酸是一种重要的平台化合物,从它出发可以合成一系列市场广阔、附加值高的产品。传统的丙烯酸化学合成法以不可再生的化石资源为原料,并对环境造成严重污染。本文从可持续发展及环境保护的角度出发,综述丙烯酸的微生物合成途径以及合成关键酶等方面的研究进展,分析探讨不同生物合成途径的优劣之处,并展望利用微生物高产丙烯酸存在的瓶颈以及有潜力的发展方向。 |
| 关键词: 丙烯酸 平台化合物 微生物催化 可再生资源 代谢工程 |
| DOI： |
| 投稿时间：2013-06-10 |
| 基金项目:广西千亿元重大科技攻关工程项目(桂科攻11107008-4),广西自然科学基金项目(2012GXNSFBA053063、2013GXNSFDA019007),广西科学研究与技术开发计划项目(桂科重12118004-3、桂科重12118004-4、桂科重1348004-5),广西科学院基本科研业务费项目(12YJ25SW01、12YJ25SW02)资助。 |
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| Advances in the Research of Acrylic Acid Production by Microbial Catalysis |
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XIE Neng-zhong, WANG Qing-yan, ZHU Qi-xia, QIN Yan, CHEN Dong, LI Yi, HUANG Ri-bo
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| (State Key Laboratory of Non-food Biomass and Enzyme Technology, National Engineering Research Center for Non-food Biorefinery, Guangxi Academy of Engineering for Biomass Industrialization, Guangxi Key Laboratory of Biorefinery, Nanning, Guangxi, 530007, China) |
| Abstract: |
| Acrylic acid,an important platform chemical with considerable value and huge market demand,is widely used in synthesizing a series of commodity chemical.Acrylic acid is conventionally produced from the petrochemical industry.Unfortunately,petrochemical carbon sources are not renewable and cause serious environmental pollution.In this review,research developments on different biosynthetic pathways and enzymes for acrylic acid,were discussed.In addition,the advantages and disadvantages of each pathway were compared and explained.Finally,the existing bottlenecks in biosynthesis of high-yield acrylic acid,and the potential development direction in this field were elucidated. |
| Key words: acrylic acid platform chemical microbial catalysis renewable carbohydrates metabolic engineering |
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