| 引用本文： |
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邓翎洁,李柳铭,翟丹梅.人类体外受精助孕治疗中多原核受精的相关因素分析[J].广西科学院学报,2013,29(2):114-116. [点击复制]
- DENG Ling-jie,LI Liu-ming,ZHAI Dan-mei.Analysis of Related Factors in Polypronuclear Fertilization during Human in vitro Fertilization Treatment[J].Journal of Guangxi Academy of Sciences,2013,29(2):114-116. [点击复制]
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| 摘要: |
| 收集2011年7月至2012年11月在广西生殖医学研究中心行体外受精助孕治疗的456例患者资料,将观察到多原核受精的235例作为多原核受精组,未观察到多原核受精的221例作为无多原核受精组,比较两组间基础卵泡刺激素(基础FSH)、黄体生成素(LH)水平、窦卵泡数(AFC),促性腺激素(Gn)总剂量及天数,HCG(人绒毛膜促性腺激素)日血清雌二醇(E2)水平、HCG日血清孕酮(P)水平、HCG日血清黄体生成素(LH)水平,HCG日大卵泡(≥14mm)数,获卵数,受精密度等助孕治疗相关指标的差异,分析人类体外受精中多原核受精的影响因素。结果提示,Gn用量小,HCG日血清E2水平较高,卵泡数及获卵数较多,受精率较高的周期中出现至少1个多原核受精合子的可能性比较大。 |
| 关键词: 体外受精 多原核受精 促性腺激素 人绒毛膜促性腺激素 卵泡数 受精率 |
| DOI： |
| 投稿时间：2013-02-16修订日期：2013-03-22 |
| 基金项目: |
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| Analysis of Related Factors in Polypronuclear Fertilization during Human in vitro Fertilization Treatment |
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DENG Ling-jie, LI Liu-ming, ZHAI Dan-mei
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| (Guangxi Reproductive Medical Center, Nanning, Guangxi, 530021, China) |
| Abstract: |
| The 456 IVF treated patients in Guangxi Reproductive Medical Center from July 2011 to November 2012 had been collected. The 235 patients observed polynucleus zygotes as polypronuclear group and the 221 patients didn't observe polynucleus zygotes as non-polypronuclear group. The differences between the two groups in basal FSH, LH level, AFC, length and dose of Gn, serum E2,P,LH in HCG day, the follicles counts (mean diameters ≥ 14mm),the numbers of obtained oocytes,sperm concentration,sperm motility,motile sperm/oocyte ratio,fertilization rate,cleaving rate,and embryos of high quality rate were analyzed. The results indicated that a higher possibility of polypronuclear observing at least one polypronuclear zygote in the cycles, higher serum E2 level,more big follicles and obtained oocytes could be achieved by the lower dose of Gn. |
| Key words: in-vitro fertilization polypronuclear gonadotropin human chorionic gonadotropin follicles counts fertilization rate |
