| 引用本文： |
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张炜,刘雯,覃洁萍.中药莪术的研究概况[J].广西科学院学报,2006,22(S1):481-486. [点击复制]
- ZHANG Wei,LIU Wen,QIN Jie-ping.Research Survey of Chinese Native Medicine Ezhu[J].Journal of Guangxi Academy of Sciences,2006,22(S1):481-486. [点击复制]
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| 摘要: |
| 近年来有关中药莪术的研究得出,莪术中主要含有莪术油、姜黄素及多糖类成分。莪术油常采用水蒸气蒸馏法和超临界流体萃取法提取,姜黄素采用乙醇回流法、多糖类采用热水浸提法提取。莪术油含量测定方法有可见分光光度法和气相色谱法等,姜黄素的含量测定方法有高效液相色谱法、薄层扫描法等,微量元素可应用等离子体发射光谱法进行测定。莪术具有抗肿瘤、抗血小板聚集、抗菌、抗病毒、抗化疗、抗白血病、抗癫痫、抗前列腺增生,促进机体免疫力,改善胃动力等作用。莪术的临床应用为莪术油相关制剂,一般包括注射液、滴眼液、软膏剂、乳剂、栓剂、霜剂、β-环糊精包合物和微球等。莪术在抗肿瘤和抗血栓方面具有广阔的开拓空间,发展前景十分诱人。 |
| 关键词: 莪术 莪术油 有效成分 含量测定 药理研究 临床应用 |
| DOI： |
| 投稿时间：2006-06-27 |
| 基金项目:广西科技厅资助项目(桂科攻0537017-6)资助 |
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| Research Survey of Chinese Native Medicine Ezhu |
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ZHANG Wei, LIU Wen, QIN Jie-ping
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| (Guangxi Traditional Chinese Medical University, Nanning, Guangxi, 530001, China) |
| Abstract: |
| The research in recent years of Chinese native medicine Ezhu reveals the main constituents in Ezhu are Ezhu oil,ginger flavine and multi-carbohydrate ingredients.Method of steam distillation and supercritical fluid extraction had been adopted to extract Ezhu oil.Method of Ethyl-alcohol backflowing had been adopted to extract ginger flavine and hot-water-lixiviating method had been adopted to extract multi-carbohydrate ingredients.UV-vis and GC are used to determine the contents of Ezhu oil.The quantitative analysis methods of ginger flavine include HPLC,TLC and so on.The trace elements in Ezhu are determined by ICE-AES.The research reveals Ezhu has many pharmacological activities,including anti-tumor,anti-platelet aggregation,against virus and bacteria,antichemical therapy,anti-leukemic,anti-epileptic,anti-benign prostatic hyperplasia,improving immune function,improving gastric dynamic and so on.Ezhu oil preparations are used in clinic including injection,eye drop,ointment,emulsion,suppository,cream,β-cyclodextrin inclusion,microsphere and so on.Ezhu has great potential in antitumor and antithrombotic effect. |
| Key words: Ezhu Ezhu oil effective composition contents determination pharmacological study clinic application |
