| 引用本文： |
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杨曦亮,王健娇,姜睿,刘永宏,周雪峰.海藻共附生真菌活性天然产物研究进展[J].广西科学,2020,27(5):462-474. [点击复制]
- YANG Xiliang,WANG Jianjiao,JIANG Rui,LIU Yonghong,ZHOU Xuefeng.Advances in Active Natural Products from Marine Alga-derived Fungi[J].Guangxi Sciences,2020,27(5):462-474. [点击复制]
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| 摘要: |
| 海藻共附生真菌次级代谢产物结构类型多样、骨架新颖、活性丰富，为新型海洋药物先导化合物的发现提供了宝贵的来源。本文以生物活性对海藻共附生真菌来源的天然产物进行分类，从抗菌、抗肿瘤、抗氧化、抗炎、浮游生物抑制等方面，对2006年以来报道的海藻共附生真菌来源的112个活性天然产物进行概述，为海藻及其共附生微生物的进一步研究与开发提供参考。 |
| 关键词: 海藻共附生真菌 次级代谢产物 天然产物 生物活性 海洋药物 |
| DOI：10.13656/j.cnki.gxkx.20201214.004 |
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| 基金项目:国家自然科学基金项目（31900286，81973235，21977102）和广东省自然科学基金杰出青年项目（2019B151502042）资助。 |
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| Advances in Active Natural Products from Marine Alga-derived Fungi |
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YANG Xiliang1, WANG Jianjiao2, JIANG Rui1, LIU Yonghong2, ZHOU Xuefeng2
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| (1.Medical College, Wuhan University of Science of Technology, Wuhan, Hubei, 430081, China;2.Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, Guangdong, 510301, China) |
| Abstract: |
| The secondary metabolites from marine alga-derived possess diverse structure types,novel skeletons and abundant activities,and provide a valuable source for the screening and discovery of new marine drug lead compounds.In this paper,we classify natural products from marine alga-derived fungi according to the types of biological activities.From the aspects of antibacterial,anti-tumor,antioxidant,anti-inflammatory,plankton inhibition,etc.,112 activities from marine alga-derived fungi reported in 2006 are summarized,which provides references for further research of marine alga and marine alga-derived microorganisms. |
| Key words: alga-derived fungi secondary metabolites natural products biological activities marine drugs |
