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  • 黄玲,陈俞婷,潘尚领,陈宁园.火麻仁化学成分、药理作用和临床应用研究进展[J].广西科学院学报,2025,41(2):157-169.    [点击复制]
  • HUANG Ling,CHEN Yuting,PAN Shangling,CHEN Ningyuan.Research Progress on Chemical Components,Pharmacological Effects and Clinical Applications of Hemp Seed[J].Journal of Guangxi Academy of Sciences,2025,41(2):157-169.   [点击复制]
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火麻仁化学成分、药理作用和临床应用研究进展
黄玲, 陈俞婷, 潘尚领, 陈宁园
0
(广西医科大学病理生理学教研室, 广西南宁 530021)
摘要:
火麻仁(Hemp seed)为桑科植物大麻(Cannabis sativaL.)的干燥成熟果实,其化学成分主要包括脂肪酸类、蛋白质类、木脂素酰胺类、甾体及萜类、黄酮及苷类、大麻素类等,具有抗氧化,抗炎,神经保护,调节血脂、血糖和血压,调节胃肠功能,抗肿瘤,抗菌等方面的药理作用,临床主要用于预防和治疗心血管疾病、神经系统疾病、糖尿病、肿瘤等。当前尚未明确其关键治疗成分,且缺乏临床试验数据支持其药理机制。本文综述火麻仁的化学成分、主要药理作用和临床应用,为其更广泛应用提供参考。
关键词:  火麻仁  化学成分  药理作用  临床应用
DOI:10.13657/j.cnki.gxkxyxb.20250722.002
投稿时间:2025-05-14修订日期:2025-06-08
基金项目:国家自然科学基金项目(82360286)和广西青年科学基金项目(2023JJB140108)资助。
Research Progress on Chemical Components,Pharmacological Effects and Clinical Applications of Hemp Seed
HUANG Ling, CHEN Yuting, PAN Shangling, CHEN Ningyuan
(Department of Pathophysiology, Guangxi Medical University, Nanning, Guangxi, 530021, China)
Abstract:
Hemp seed is the dried mature fruit of Cannabis sativa L..The chemical constituents of hemp seed mainly include fatty acids,proteins,lignanamides,steroids and terpenoids,flavonoids and glycosides,cannabinoids,etc. It has the pharmacological effects of anti-oxidation,anti-inflammation,neuroprotection,regulation of blood lipids,blood glucose and blood pressure,regulation of gastrointestinal function,anti-tumor,antibacterial and so on. Clinically,it is mainly used to prevent and treat cardiovascular diseases,nervous system diseases,diabetes,tumors and so on. At present,its key therapeutic components have not been clarified,and there is a lack of clinical trial data to support its pharmacological mechanism. This article reviews the chemical components,main pharmacological effects and clinical application of hemp seed,and provides a reference for its wider application.
Key words:  hemp seed  chemical components  pharmacological effects  clinical applications

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