| 引用本文： |
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易湘茜,高程海,易蔚.红树无瓣海桑果实中抗氧化活性成分研究[J].广西科学院学报,2013,29(4):217-219,223. [点击复制]
- YI Xiang-xi,GAO Cheng-hai,YI Wei.Antioxidant Compounds from the Fruit of the Mangrove Plant Sonneratia Apetala[J].Journal of Guangxi Academy of Sciences,2013,29(4):217-219,223. [点击复制]
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| 摘要: |
| 从红树无瓣海桑果实中分离出6个化合物,运用波谱学确定了化合物结构,分别鉴定为异鼠李素(1),胡萝卜苷(2),木栓酮(3),熊果酸(4),3,4-二羟基苯甲酸(5),对-羟基-3-甲氧基苯甲酸(6)。化合物(1),(3),(4)对HepG2显示出抗氧化活性,其EC50值分别为(25.8±1.3) mM,(62.1±3.5) mM,(45.2±2.8) mM。化合物(1)~(6)均首次从该植物果实中分离得到。 |
| 关键词: 红树 无瓣海桑 化学成分 抗氧化活性 |
| DOI： |
| 投稿时间：2013-07-18修订日期：2013-08-05 |
| 基金项目:广西高等学校特色专业及课程一体化项目(GXTSZY214);广西中医药大学科研项目(P12041);广西自然科学基金项目(2011GXNSFB018035,2011GXNSFE018002,2012GXNSFAA-053160,2012GXNSFEA053001)资助。 |
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| Antioxidant Compounds from the Fruit of the Mangrove Plant Sonneratia Apetala |
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YI Xiang-xi1, GAO Cheng-hai2, YI Wei1
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| (1.Faculty of Pharmacy, Guangxi University of Chinese Medicine, Nanning, Guangxi, 530001, China;2.Guangxi Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China) |
| Abstract: |
| The chemical constituents,from the fruit of Sonneratic Apetala,and their antioxidant activity were studied. Six compounds were isolated by the EtOH-CH2Cl2 (2:1) extract of air-dried fruit and identified by CC,PTLC and HPLC.These compounds were characterized by comparison of their physical and spectral data (1H NMR, 13C NMR and MS). Antioxidant activity bioassay indicated that compounds 1,3 and 4 had moderate cytotoxicity toward human cancer cell line HepG2.In addition,it is also the first time that all these compounds were isolated from the fruit of this plant. |
| Key words: mangrove Sonneratic Apetala compound antioxidant activity |
