| 引用本文： |
-
朱其芳,梁浩.急性脑梗死患者血清LPO、SOD和GSH-Px含量的改变和临床意义[J].广西科学院学报,1998,(3):35-36,39. [点击复制]
- Zhu Qifang,Liang Hao.Changes of LPO, SOD and GSH-Px Concentration in Serum of Cerebral Infarction Patients and Their Significance[J].Journal of Guangxi Academy of Sciences,1998,(3):35-36,39. [点击复制]
|
|
| 摘要: |
| 探讨脑梗死患者体内自由基含量的改变及其与脑缺血损伤的关系,为临床治疗提供一定的理论依据。我们对27例急性脑梗死患者血清LPO、SOD和GSH-Px进行测定,并与对照组进行比较,结果显示病人组LPO含量和LPO/SOD比值明显高于对照组,SOD含量明显低于对照组,GSH-Px含量和LPO/GSH比值与对照组无显著差异,提示自由基反应参与脑缺血损伤过程。 |
| 关键词: 脑梗死 过氧化脂质(LPO) 超氧化物歧化酶(SOD) 谷胱甘肽过氧化物酶(GSH-Px) |
| DOI： |
| 投稿时间：1998-02-16修订日期：1998-06-18 |
| 基金项目: |
|
| Changes of LPO, SOD and GSH-Px Concentration in Serum of Cerebral Infarction Patients and Their Significance |
|
Zhu Qifang1, Liang Hao2
|
| (1.Teaching and Research Section of Biochemistry, Guangxi Medical University, 530021;2.Guangxi People Hospital, Nanning, 530021) |
| Abstract: |
| This study was to discuss the changes of free radical in cerebral infarction patients and the relationship between free radical and cerebral injury and to afford theoretical basis for clinical treatment.We assayed LPO,SOD and GSH-Px concentration in serum of 27 patients with cerebral infarction.The result showed that the concentration of LPO and LPO/SOD ratio in serum of patient group were significantly higher than that of control group and SOD was lower.The concentration of GSH-Px and LPO/GSH-Px ratio in serum had no significant difference compared with control group.Our results support that the free radical reaction may take part in the developing of cerebral ischemia injury. |
| Key words: cerebral infarction LPO SOD GSH-Px |
