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  • 窦慧宏,龙桂芳.血清转铁蛋白受体的研究进展及临床意义[J].广西科学,2006,13(2):139-142,146.    [点击复制]
  • DOU Hui-hong,LONG Gui-fang.Progress of the Study on the Serum Transferrin Receptor and the Significance of Clinic[J].Guangxi Sciences,2006,13(2):139-142,146.   [点击复制]
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血清转铁蛋白受体的研究进展及临床意义
窦慧宏, 龙桂芳
0
(广西医科大学第一附属医院儿科, 广西南宁 530021)
摘要:
血清转铁蛋白受体(sTfR)是完整的细胞受体的一个可溶性节段,通过酶免疫法或免疫浊度法可从血清中检出。sTfR反映机体贮存铁的数量以及所需铁的数量,是判断机体是否缺铁的一项敏感指标。sTfR可以定量评价骨髓幼红细胞的生成,尤其适用于评价各类骨髓红系显著增生的溶血性贫血。
关键词:  血清转铁蛋白受体  研究进展  临床意义
DOI:
投稿时间:2005-08-17修订日期:2005-11-07
基金项目:
Progress of the Study on the Serum Transferrin Receptor and the Significance of Clinic
DOU Hui-hong, LONG Gui-fang
(Department of Peadiatric, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China)
Abstract:
The serum transferrin receptor is a new field about the study of the transferrin receptor.As a result of TfR cleavage from the cell surface, soluble TfR (sTfR) can be detected in the serum by Enzyme Linked Immunosorbent.The inspection of sTfR is convenient, so the level of serum transferrin receptor is supposed to be a useful indicator of the stored iron and the functional iron, it is a sensitive indicator of tissue iron deficiency.sTfR also can be a valuable quantitative assay of bone marrow erythroblast, especially to the hemolytic anemia with erythroid hyperplasia.
Key words:  serum transferrin receptor  advancement of investigation  significance of clinic

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