| 引用本文： |
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刘义,龙盛京,谢云峰.茵陈等六种中药对肝葡萄糖醛酸转移酶的体外诱导作用[J].广西科学,1994,1(4):57-58. [点击复制]
- Liu Yi,Long Shengjin,Xie Yunfeng.Effects of Artemisia capillaris and Other Five Chinese Medicinal Herbs on the Activity of Rat Liver UDP-glucuronyltransferase[J].Guangxi Sciences,1994,1(4):57-58. [点击复制]
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| 摘要: |
| 为了解中药治疗新生儿黄疸是否通过酶的诱导作用,用洋地黄皂甙作为体外肝葡萄糖醛酸转移酶(UGT)诱导的阳性对照物。用Black法测定茵陈(Artemisia capillaris)、黄连(Coptis chinensis)、大黄(Rheum officinale)、黄芩(Scutellaria baicalensis)、栀子(Fructus gardeniae)及甘草(Glycyrrhiza glabra)的水提物对Wistar大鼠肝匀浆在体外UGT酶诱导作用。结果表明,在体外实验,这6种中药水提取物不能增加大鼠肝细胞中UGT的活性。 |
| 关键词: 葡萄糖醛酸转移酶 中药水提物 动物实验 新生儿黄疸 |
| DOI： |
| 投稿时间：1984-08-09 |
| 基金项目:国家自然科学基金 |
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| Effects of Artemisia capillaris and Other Five Chinese Medicinal Herbs on the Activity of Rat Liver UDP-glucuronyltransferase |
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Liu Yi, Long Shengjin, Xie Yunfeng
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| (Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021) |
| Abstract: |
| For making sure that the treatment of neonatal jaundice with Chinese medicinal herbs is whether by induction of enzyme, the induction of Wistar rat liver uridinediphosphate glucuronyltransferase (UDP-GT) in vitro with the water extractives of six Chinese medicinal herbs,Artemisia capllaris,Coptis chinensis, Fructus srardeniae, Rheum officinale,Scutellaria baicalensis and Glycyrrhiza glabra were measureed by Black's method. Digitonin was used as a positive enzyme-induced agent. The results showed that there were no difference between these herbs and blank control. |
| Key words: glucuronyltransferase Chinese medicinal herb water extractive animal experiment neonatal jaudice |
